منابع مشابه
Bioreactor Design for Chemical Engineers
Fermentation — the essence of bioprocessing — predates the discipline of chemical engineering by thousands of years. Ancient civilizations used bioprocessing to create such useful and tasty items as beer, wine, sauerkraut, kim-chi, and cheese. Until the discovery of penicillin and its commercialization in 1943, bioprocessing was not performed on an industrial scale with equipment resembling tha...
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As per definition, the bioreactor is the designed space where biological reactions take place. Hence, the bioreactor is essentially an engineering achievement and its design a challenge for bioengineers. The bioreactor should create a biosphere that as profoundly and adequately as possible provides the ideal environment for the biological reaction. The path for reaching, attaining, andmaintaini...
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Rahul Kumar, Junior, Columbia University Mentors: Sharan Ramaswamy Ph.D., University of Pittsburgh Michael Sacks Ph.D. University of Pittsburgh Introduction: A bioreactor that is capable of cyclic flexure, stretch, and flow (FSF) has been previously designed and built by Engelmayr et al [1]. The bioreactor is used to implement mechanical stimuli on engineered heart valve tissue [2]. In this mec...
متن کاملBioreactor Design Geometry Effects on Nitrate Removal
Denitrification bioreactors for nitrate removal in agricultural drainage have recently gained attention for their low cost and effectiveness. While research continues to investigate the optimal sizing of these systems, little work has been done on the optimal design geometry (Length to width ratio and cross sectional shape). To address this lack, pilot-scale (1/10th scale) work performed in Iow...
متن کاملDesign modification and optimisation of the perfusion system of a tri-axial bioreactor for tissue engineering
A systematic design of experiments (DOE) approach was used to optimize the perfusion process of a tri-axial bioreactor designed for translational tissue engineering exploiting mechanical stimuli and mechanotransduction. Four controllable design parameters affecting the perfusion process were identified in a cause-effect diagram as potential improvement opportunities. A screening process was use...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1995
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(95)90811-0